Sensory Enrichment Therapy can support the treatment of

Angelman Syndrome

Angelman Syndrome (AS) is a rare genetic disorder that affects the nervous system, leading to developmental delays, severe speech impairments, movement and balance issues, and frequent smiling and laughter.

Individuals with AS often require lifelong support to manage their symptoms and improve their quality of life.

Sensory Enrichment Therapy is very effective in helping regulate the brain’s chemistry.

Sensory Enrichment Therapy aims at re-wiring other key brain functions affected in Angelman Syndrome, including speech development, memory, fine and gross motor skills and sleep.

How Sensory Enrichment Therapy Supports Individuals with Angelman Syndrome

At Mendability, we believe in the brain’s incredible capacity to grow and adapt.

Our Sensory Enrichment Therapy is designed to stimulate brain development and improve brain function through carefully crafted sensory activities.

Improved Communication

So far, research on Angelman Syndrome (AS) has revealed that speech impairments are primarily due to the genetic and neurological disruptions caused by the deletion or mutation of the UBE3A gene on chromosome 15.

This gene plays a crucial role in the normal functioning of neurons, particularly in the brain regions involved in motor control, learning, memory, and communication.

Motor control, learning, memory and communication are functions of the brain where we can stimulate development.

In clinical studies, it has been shown that Sensory Enrichment therapy can improve communication in 6 months by an average of 10%.

This means that in a year, what used to be a major problem is now a minor problem, or what was a minor problem is now maybe a problem.

Enhanced Motor Skills:

Our sensory enrichment activities are designed to improve coordination, balance, and fine motor skills by creating new connections in the brain through novel sensory experiences.

Below are the improvements measured in motor skills in 1,002 children aged 1 to 18, after 6 months of Sensory Enrichment Therapy. The study was published in Neural Plasticity in 2016.

Better Sleep Patterns

Sleep disturbances are common in individuals with AS. Our program includes sensory activities that help regulate the brain’s sleep-wake cycle, promoting better sleep quality and duration.

Below are the improvements measured in sleep patterns in 1,002 children aged 1 to 18, after 6 months of Sensory Enrichment Therapy. The study was published in Neural Plasticity in 2016.

Reduced Anxiety and Behavioral Challenges

Individuals with Angelman Syndrome may experience heightened anxiety and behavioral issues. Sensory Enrichment Therapy helps calm the brain by regulating sensory input, leading to a more balanced emotional state and a reduction in challenging behaviors.

Below are the improvements measured in anxiety and behavior in 1,002 children aged 1 to 18, after 6 months of Sensory Enrichment Therapy. The study was published in Neural Plasticity in 2016.

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“This is really working! My toddler has started using functional language!

His cognition has improved, his motor skills are getting way better, he is finally starting to climb and point and wave and able to copy signs. He has been blossoming intensely, really catching up at a faster rate. Now we have SO much hope!”

– Melissa M. (New Zealand)

parent of a 3-year-old boy

“I think that [my son] is responding great to the therapy! He definitely seems to be following instructions better across the board and is just a little more aware of the world around him.

We have also seen some improvements in speech, pronunciation, eating, handwriting and overall function.”

– Sara J. (California)

parent of a 4-year-old boy

“I went to the library where we spent about 2 hours, and both of the girls were happily reading while staying in their seats. In our prior visits, the oldest one just roamed and ran around the library while I chased her. This time, I was pleasantly surprised by how long my oldest daughter (4) sat and stayed focus on reading. This has never happened before!”

– Mary M. (Texas)

parent of a 4-year-old-girl

The top 5 areas where parents report the most improvements in the first few weeks are Sleep, Eating, Social Skills, Attention and Sensory Processing

Tailored enrichment therapy is designed to boost brain plasticity in targeted brain functions

• Emotion (motivation to engage with other people),

• Self-awareness (where do I fit in space and this social world?),

• Fine motor (can I control my voice box, lips, breathing, etc.?),

• Auditory processing (can I hear myself speak?),

• Memory and learning (vocabulary, sentence structure),

• Mental image (can I picture what I want to say in my mind?), etc.

As these tools improve in the brain, the bottlenecks that slowed down natural speech development should fade away.

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